Shinjuku
The busiest interchange in the city wrapped in department stores, offices, izakaya alleys, a large park and a nightlife quarter, all within a few minutes of one another.
Almost every line in western Tokyo passes through, plus airport buses and express trains towards the mountains.
Best for: a first visit and the shortest average journey to anywhere. Strength: unbeatable connections and everything open late. Watch out for: crowds, noise and a station complex that takes real time to learn.
Shibuya
Youth-driven and commercial around the crossing, then immediately calmer up the hills towards Tomigaya, Yoyogi-Uehara and the park.
A major hub for city and suburban lines, and an easy walk to Harajuku, Omotesando and Yoyogi Park.
Best for: shopping, cafés, nightlife and walkable evenings. Strength: energy and variety on foot. Watch out for: price levels, weekend crowds and hills with stairs everywhere.
Tokyo Station & Marunouchi
Corporate, spacious and orderly: wide avenues, the Imperial Palace gardens on one side and a huge underground retail and dining network below.
The Shinkansen gateway and the best base for day trips out of the city, with direct airport access.
Best for: day trips, business travel and a calm night's sleep. Strength: unmatched onward connections and space. Watch out for: an area that empties in the evening and higher room rates.
Ginza & Nihonbashi
The polished, expensive side of the city: flagship stores, long-established restaurants, galleries and department-store food halls.
Central and well connected by metro, and walkable to Tsukiji, Hibiya and the bay side.
Best for: dining, premium shopping and a central, quiet base. Strength: quality and location. Watch out for: the highest prices in the city and little street life late at night.
Asakusa & Ueno
Older, lower and more traditional: temple streets, a big park with major museums, market arcades and long-standing local restaurants.
Direct rail towards Narita and the north, but further from the western nightlife districts.
Best for: value, culture and families. Strength: the lowest central room rates and the most traditional streets. Watch out for: earlier closing times and a longer trip to Shibuya or Shinjuku.
Shinagawa
A business and transit district: hotel towers, office blocks and restaurants built around a very large station rather than a neighbourhood.
Fast direct access to Haneda Airport and a Shinkansen stop for travel west.
Best for: a short trip, an early flight or frequent travel out of the city. Strength: speed to the airport and onward trains. Watch out for: little neighbourhood character and a functional, corporate feel.
Nakameguro & Daikanyama
Low-rise, residential and design-minded: a canal lined with cherry trees, independent shops, coffee and small restaurants instead of department stores.
One or two stops from Shibuya, with good lines but fewer late-night options than the hubs.
Best for: a calmer stay with real neighbourhood life. Strength: atmosphere and everyday quality. Watch out for: high rents, small units and fewer budget options.
Kichijoji & Nakano
Western Tokyo living: covered shopping streets, a large park, supermarkets, schools and everyday prices, with the centre a straight train ride away.
Direct lines into Shinjuku in roughly a quarter of an hour, though the trains are crowded at peak times.
Best for: a month or longer at ordinary prices. Strength: space, value and a genuine local routine. Watch out for: a daily commute and less English support than the central hubs.